Pharmacology of Organic Cation Transporters: Focus on Structure-Function Relationships in OCT3 (SLC22A3)
نویسندگان
چکیده
5 GENERAL INTRODUCTION 7 MATERIALS AND METHODS 13 PART I: POLYAMINE TRANSPORT BY POLYSPECIFIC OCT1, OCT2, AND OCT3
منابع مشابه
Synchronized activity of organic cation transporter 3 (Oct3/Slc22a3) and multidrug and toxin extrusion 1 (Mate1/Slc47a1) transporter in transplacental passage of MPP+ in rat.
The aim of the present study was to investigate the expression, localization, and function of organic cation transporter 3 (Oct3, Slc22a3) and multidrug and toxin extrusion protein 1 (Mate1, Slc47a1) in the rat placenta. Using qRT-PCR and Western blotting techniques, we demonstrated abundant Oct3 and Mate1 mRNA and protein expression achieving significantly higher levels than those in the mate...
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